Amitriptyline belongs to a group of medicines known as tricyclic antidepressants
Regarding cardiovascular changes following the use of amitriptyline, amitriptyline usage is associated with significant prolongation of QRS and QTc as well
John A
Bradyarrhythmias are broadly classified as sinus node dysfunction and atrioventricular block
The non-FDA approved indications are anxiety, post-traumatic stress disorder, insomnia, chronic pain (diabetic neuropathy
Diagnosis & treatment
Amitriptyline is a widely prescribed tricyclic antidepressant (TCA) with a very concerning cardiotoxicity profile, but it is one that has not been discussed much in
J Am Coll Cardiol 2024;83:932-950
It results from occlusion of the coronary arteries and results in a demand-supply
27th Bethesda Conference: matching the intensity of risk factor management with hazard for coronary disease events
Cardiomyopathy is a disease that enlarges and weakens the heart muscle, making it harder for the heart to pump blood to the rest of the body
The most important adverse cardiovascular events include cardiovascular death, myocardial infarction (MI), and stroke
amantadine, amiodarone, amisulpride, amitriptyline, amphetamine, anagrelide, apomorphine Coronary Artery Disease (CAD) Coronary artery disease is caused by plaque buildup in the wall of the arteries that supply blood to the heart (called coronary arteries)
Symptoms of overdosage may include dry mouth, coma of varying degree, hypotension, hypothermia, hyperreflexia, extensor plantar responses, convulsions, respiratory failure, cardiac conduction defects, and arrhythmias
Cilostazol is also indicated for secondary prevention in patients with a history of transient ischemic attacks or non-cardioembolic ischaemic stroke
Thought to exert an analgesic effect on the visceral component associated with cardiac pain
It is also sometimes called coronary artery disease or ischemic heart disease
sweating
With CAD, plaque first grows within the walls of the coronary arteries until the blood flow to the heart’s muscle is limited, which prevents the heart muscle from receiving enough oxygen
Medications
Background: To assess use of antidepressants by class in relation to cardiology practice recommendations, and the association of antidepressant use with the occurrence of major adverse cardiovascular events (MACE) including death
Coronary artery disease (CAD) is still an important cause of morbidity and mortality despite advanced medical and interventional therapies
It is the leading cause of death in the United States in both men and women
13 Among patients with cardiovascular disease, unstable angina (UA) and myocardial infarction (MI) are severe, life-threatening conditions that represent sudden myocardial ischemia (loss of blood flow to the heart muscle, with