Androgens Androgen excess is often associated with obesity states, at any age of life, because of changes in the pattern of secretion or metabolism of androgens and in their
The co-existence of
The
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Excess accumulation of adipose tissue in the central region of the body (intra-abdominal, “android,” or male-pattern obesity) correlates with increased risk of and
The main circulating androgen is testosterone, which is produced in the Leydig
The activities of the 5 alpha-reductase (the enzyme that converts testosterone into dihydrotestosterone, DHT), and of the 3 alpha-hydroxysteroid dehydrogenase (the 1
They are responsible for pregnancy, puberty, menstruation, menopause, sex drive, sperm production and more
Androgens have been shown to be effective in many uterine diseases; however, the side effects of androgens have limited their use in women’s diseases
The microbiota plays a major role in the reproductive endocrine system throughout a woman’s lifetime by interacting with estrogen, androgens, insulin, and other hormones
, 2008)
These correlations are amplified by higher levels of abdominal fat seen in obesity and post-menopause
The increased obesity occurs in both obese and non-obese women
this seems to constitute a metabolic group of conditions which are thus associated with BMI
, estrogens, progesterone, and testosterone) as well as the adrenal gland (e
In people assigned male at birth (AMAB), androgens typically support: vocal cord lengthening/voice deepening